Forensic Microscope
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Other Articles:
| • | Scientists induce chirality in pre-biological molecules |
| The creation of chirality from the elementary building blocks of matter is one of the great mysteries of the origin of life. Scientists at the U.S. Department of Energy's Argonne National Laboratory have discovered a way to induce this handedness in pre-biological molecules. | |
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| • | Human (Homo sapiens) |
| Can we determine what separated humans and animals and define classification to better help humans understand their place in the animal kingdom hierarchy? One researcher plans on doing just that in the “What Makes Humans Unique” project. | |
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| • | Ultrasound Waves Aid In Rapid Treatment Of Deep Vein Thrombosis |
| The use of ultrasound waves for deep vein thrombosis may help dissolve blood clots in less time than using clot-busting drugs alone, according to researchers. |
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| • | Crowding in European forests: a review of recent research and implications for forest management and policy |
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This paper analyses and summarizes European research dealing with forest visitors’ crowding perceptions. Compared with recreation research in North America, where crowding is an important topic, only 16 European crowding studies have been identified since the 1980s. Their focus lies on everyday users in rural and urban forest settings of Central and Northern Europe. In these studies between 10 and 64 per cent of the respondents perceived crowding. Most studies used the same theoretical foundation oriented towards US recreation crowding literature but differed in their methods of measuring crowding. As a result, the use of different scales and data collection methods restrict a nation- and Europe-wide comparison. There is a need for standardized crowding research in order to gain insights into cultural differences and commonalities for integrating forest recreation management into a sustainable framework for forest management. |
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| • | Introduction to shock |
| What causes shock and how to identify it | |
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| • | The fusidic acid stimulon of Staphylococcus aureus |
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Fusidic acid interferes with the release of elongation factor G (EF-G) after the translocation step of protein synthesis. The objective of this study was to characterize the fusidic acid stimulon of a fusidic acid-susceptible strain of Staphylococcus aureus (SH1000). S. aureus microarrays and real-time PCR determined transcriptome alterations occurring in SH1000 grown with fusidic acid. The Staphylococcus aureus microarray meta-database (SAMMD) compared and contrasted the SH1000 fusidic stimulon with 89 other S. aureus transcriptional datasets. Fusidic acid gradient analyses with mutant-parent strain pairs were used to identify genes required for intrinsic fusidic acid susceptibility identified during transcriptional analysis. Many genes altered by fusidic acid challenge are associated with protein synthesis. SAMMD analysis determined that the fusidic acid stimulon has the greatest overlap with the S. aureus cold shock and stringent responses. Six out of nine peptidoglycan hydrolase genes making up the two component YycFG regulon were also up-regulated by fusidic acid, as were a carboxylesterase gene (est) and two putative drug efflux pump genes (emr-qac1 and macA). Genes down-regulated by fusidic acid induction encoded a putative secreted acid phosphatase and a number of protease genes. Roles for the agr operon, the peptidoglycan hydrolase gene isaA and two proteases (htrA1 and htrA2) in the expression of fusidic acid susceptibility were revealed. The SH1000 fusidic acid stimulon includes genes involved with two stress responses, YycFG-regulated cell wall metabolism, drug efflux, and protein synthesis and turnover. |
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By michael@nanowerk.com (Michael Berger) - Copyright 2005-2008 Nanowerk LLC - version: v1.5 build A